[Remote] Vice President, Commercial Operations and Strategy

Note: The job is a remote job and is open to candidates in USA. Esperion is a fully remote based company focused on delivering innovative medicines. The VP, Commercial Operations and Strategy will lead the development of a scalable commercial operating model and oversee core commercial enablement functions to enhance performance across the organization.

Responsibilities

• Lead a newly created Commercial Analytics function, setting strategy, priorities, and ways of working to ensure timely, actionable insights that inform commercial and enterprise decisions
• Serve as the primary owner of commercial decision support for the CCO and Commercial Leadership Team, translating complex data into clear recommendations on growth opportunities, risks, and trade‑offs
• Own the commercial data and analytics strategy, including evaluation, integration, and governance of internal and external data sources (e.g., CRM, claims, prescription, payer, promotional, and field activity data)
• Establish and evolve a scalable analytics framework that supports performance management, scenario planning, and long‑range strategic decision‑making
• Ensure analytical rigor, data consistency, and clear interpretation of insights across Sales, Marketing, Market Access, and Finance
• Enable a single‑source‑of‑truth mindset for commercial performance reporting and executive readouts
• Design, assess, and continuously optimize sales force size, structure, and deployment models based on demand drivers, productivity, coverage needs, and portfolio evolution
• Lead segmentation, targeting, and alignment strategies in partnership with Sales and Marketing to ensure efficient and effective field resource deployment
• Define and monitor key commercial effectiveness metrics (e.g., reach, frequency, call quality, territory productivity) and identify opportunities to improve impact and efficiency
• Lead post‑launch and post‑initiative effectiveness assessments to inform future investment and resource allocation decisions
• Foster a culture of disciplined measurement, ROI thinking, and continuous improvement across the commercial organization
• Own the commercial operating cadence, including performance reviews, business reviews, and executive‑level reporting that drive accountability and decision‑making
• Partner closely with Finance to support annual planning, budgeting, latest estimates, and performance variance analyses for commercial leadership
• Provide leadership for sales incentive compensation strategy, design, and execution, ensuring alignment with brand strategy, compliance requirements, and enterprise objectives
• Oversee territory alignment operations, CRM, and field enablement processes, ensuring usability, adoption, and high‑quality data
• Lead sales communications processes and manage the integrated Commercial Calendar (e.g., sales meetings, conventions, strategic reviews)
• Ensure strong operational discipline, governance, and coordination across commercial vendors and partners
• Lead the Sales Training and Leadership Development function, setting strategy and direction aligned to brand priorities, field needs, and organizational capabilities
• Partner with Sales Leadership and Marketing to design and deliver onboarding and ongoing training programs for field and internal commercial teams
• Oversee development of training curricula across product/market knowledge, selling skills, customer engagement models, and leadership capabilities
• Ensure training approaches evolve with changes in strategy, portfolio, and market dynamics
• Champion consistent execution, capability building, and professional development across the commercial organization
• Lead and develop high‑performing Analytics and Training teams, setting clear priorities, development plans, and performance expectations
• Operate effectively in a remote, matrixed environment, influencing across functions and levels
• Quickly assess organizational dynamics and establish credibility as a trusted advisor to commercial and enterprise leadership
• Balance strategic thinking with tactical execution, particularly in a lean organization

Skills

• Bachelor's degree required
• 20+ years of experience in the pharmaceutical or biopharmaceutical industry in a variety of commercial roles of increasing scope and responsibility
• Deep expertise in Commercial Operations, Analytics, and/or Sales Operations
• Demonstrated experience leading Commercial Operations, Analytics and/or Training functions and supporting senior leadership decision‑making
• Strong strategic mindset with the ability to translate strategy into practical, scalable execution
• Proven ability to lead through complexity, manage multiple priorities, and influence in a matrix environment
• Excellent comm

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