Scientist - Single-cell Genomics and Bioinformatics

Position: Scientist I - Single-cell Genomics and Bioinformatics Scientist I – Single-cell genomics and bioinformatics – Molecular Genetics We seek an exceptional Scientist I who will work in the Molecular Genetics department on analysis of single-cell transcriptomics and spatial transcriptomics data in the peripheral nervous system. The candidate should have an exceptionally strong background in bioinformatics and single-cell genomics, and be capable of working independently and collaboratively. They will analyze various single‑cell genomics data to define neuronal types, interrogate functional connectivity, and help design genetic tools to access these cell types. Essential Functions

• Support initiatives across the Allen Institute to create reference atlases for cells in the peripheral nervous system using single‑cell genomic data.
• Apply and adapt computational and experimental approaches to integrate gene expression and epigenetic information from a variety of single‑cell genomic datasets.
• Collaborate with team members to interpret biological findings from data and contribute ideas for follow‑up experiments, gaining independence and autonomy over time.
• Learn and apply analytical methods for defining cell types and predicting enhancer activity from single‑cell data and for supporting the development of genetic tools that mark distinct functional or anatomical cell types.
• Contribute to computational method development for single‑cell genomics, under the guidance of team leads.
• Present research findings regularly to internal team members and stakeholders; contribute to the preparation of manuscripts, grant proposals, and external presentations.

Required Education And Experience

• Ph.D. in Bioinformatics, Genomics, Neuroscience or related field; or equivalent combination of degree and experience.
• Demonstrated experience with single‑cell genomics analysis or large‑scale data analysis.
• Proficiency in programming languages and tools (R, Python, cloud computing).
• Proficiency in AI tool use, and interest in AI tool development.

Preferred Education And Experience

• Experience in reproducibly analyzing large single‑cell and spatial genomics datasets.
• Experience integrating spatial data with single‑cell genomics approaches.
• Ability to work independently and within a collaborative, multi‑disciplinary environment to meet demanding timelines.
• Positive attitude, self‑motivated, and demonstrated ability to creatively troubleshoot.
• Proven strong publication record.
• Knowledge of mouse molecular genetics, neuroscience, and neuroanatomy.
• Exceptional oral and written communication and organizational skills.

Physical Demands

• Fine motor movements in fingers/hands to operate computers and other office equipment.

Position Type/Expected Hours of Work

• This role is currently able to work both remotely and onsite in a hybrid work environment. The primary work location for all employees is 615 Westlake Ave N.; any remote work must be performed in Washington State.

Travel

• Attendance and participation in national and international conferences is required.

Annualized Salary Range $86,500 - $106,100 (final salary depends on required education, experience, and level of skills, as well as work location).

Benefits

• Employees (and their families) are eligible to enroll in benefits per eligibility rules outlined in the Allen Institute’s Benefits Guide, including medical, dental, vision, and basic life insurance. Employees are also eligible to enroll in the 401k plan. Paid time off is available per the Benefits Guide, which can be found at (Use the "Apply for this Job" box below)..

It is the policy of the Allen Institute to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by federal, state or local law. The Allen Institute will provide reasonable accommodations for qualified individuals with disabilities. #J-18808-Ljbffr Apply tot his job Apply To this Job